Mechanisms of lysine-induced acute renal failure in rats
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چکیده
منابع مشابه
Protective Effects of Crocin against Cisplatin-Induced Acute Renal Failure and Oxidative Stress in Rats
Background. The major side effect of cisplatin, used in some tumours, is nephrotoxicity. Reactive oxygen species and oxidative damage are the most important factors in cisplatin-induced acute renal failure. The main purpose of this study is to investigate the protective effects of crocin against cisplatin-induced acute renal failure and oxidative stress in rat. Methods. In this study, animal...
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The present study was aimed to evaluate the beneficial effect of Cystone syrup in an experimental model of glycerol-induced acute renal failure (ARF) in rats. Biochemical parameters, kidney weight and histopathological evaluation were performed to conclude the beneficial effect of Cystone syrup. Administration of single dose of 50% v/v glycerol (8ml/kg.i.m) caused severe renal dysfunction assoc...
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Background: Previous studies have shown increases in endothelin (ET) concentration of plasma and renal tissues in acute renal failure (ARF). ET has a potent vasoconstrictor effect, through binding with its ETA receptors, and may play some roles in renal hemodynamic dysfunction in ARF.Objective: To examine the beneficial effect of a selective ETA-receptor antagonist on renal dysfunction and tis...
متن کاملMechanisms of acute renal failure.
Acute renal failure can be defined as an abrupt decline in renal function with a decrease in glomerular filtration rate (GFR) resulting in the retention of nitrogenous waste products. Acute renal failure has conventionally been classified as (a) prerenal failure, denoting a disorder in the systemic circulation that causes renal hypoperfusion. Implicit in the prerenal classification is that the ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1985
ISSN: 0085-2538
DOI: 10.1038/ki.1985.41